Treatment of dermatophyte toenail onychomycosis with itraconazole
نویسندگان
چکیده
منابع مشابه
Liver failure and transplantation after itraconazole treatment for toenail onychomycosis.
Three weeks after completing a 4-pulse course of itraconazole for toenail onychomycosis, a 25-year-old woman patient developed severe liver crisis and required an emergency liver transplant. We report the case and discuss the use of itraconazole in onychomycosis and dermatomycoses.
متن کاملItraconazole pulse therapy for dermatophyte onychomycosis in children.
BACKGROUND Onychomycosis, or fungal infection of the nail, can occur in prepubertal children. However, its diagnosis is often missed or the condition is inappropriately treated with topical medication. Griseofulvin has been the therapy of choice, but even long-term treatment is associated with a poor cure rate and high rate of relapse. Trials with adult patients have shown that itraconazole pul...
متن کاملShort term treatment of dermatophyte onychomycosis with terbinafine.
OBJECTIVE To evaluate the effect of short term treatment with terbinafine on dermatophytosis. DESIGN Multicentre, randomised, double blind placebo controlled trial of 250 mg/day terbinafine for 12 weeks in dermatophyte onychomycosis. SETTING Eight dermatology centres in the United Kingdom. PATIENTS 112 patients (mean age 44, range 19-78), 99 with mycologically proved toenail infections an...
متن کاملDouble blind, randomised study of continuous terbinafine compared with intermittent itraconazole in treatment of toenail onychomycosis. The LION Study Group.
OBJECTIVE To compare the efficacy and safety of continuous terbinafine with intermittent itraconazole in the treatment of toenail onychomycosis. DESIGN Prospective, randomised, double blind, double dummy, multicentre, parallel group study lasting 72 weeks. SETTING 35 centres in six European countries. SUBJECTS 496 patients aged 18 to 75 years with a clinical and mycological diagnosis of d...
متن کاملA case of toenail Onychomycosis with Scopulariopsis Brevicalis
During 12 months survey on 33 patients with onychomycosis, only one of them showed infection due to scopulariopsis brevicalis. The case was a 38-year-old male with great toe nail lesion which was diagnosed as Trichophyton rubrum based on smear and culture. The patient was treated with 3 weekly pulses of itraconazole, 200mg twice daily during 3 months and showed marked clinical improvement. But ...
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ژورنال
عنوان ژورنال: International Journal of Basic & Clinical Pharmacology
سال: 2016
ISSN: 2279-0780,2319-2003
DOI: 10.18203/2319-2003.ijbcp20164754